Cartilage-inspired, lipid-based boundary-lubricated hydrogels

doi:10.1126/science.aay8276

GSTDTAP > 气候变化

DOI	10.1126/science.aay8276
	Cartilage-inspired, lipid-based boundary-lubricated hydrogels
	Weifeng Lin; Monika Kluzek; Noa Iuster; Eyal Shimoni; Nir Kampf; Ronit Goldberg; Jacob Klein
	2020-10-16
发表期刊	Science
出版年	2020
英文摘要	In engineered systems, a reduction in friction can come from the use of lubricants or through surface coatings that are inherently slippery. For most hydrogels, which are cross-linked polymers heavily swelled with water, surface lubrication typically comes from trapped liquids that help to form a slippery surface. Drawing inspiration from articular cartilage that in part uses a lipid boundary layer, Lin et al. designed hydrogels with small concentrations of lipids that are continuously exuded toward the surface to make a slippery layer (see the Perspective by Schmidt). Friction and wear of the hydrogels was reduced by up to a factor of 100, and the effect was observed even after the hydrogels were dried and rehydrated. Science , this issue p. [335][1]; see also p. [288][2] The lubrication of hydrogels arises from fluid or solvated surface phases. By contrast, the lubricity of articular cartilage, a complex biohydrogel, has been at least partially attributed to nonfluid, lipid-exposing boundary layers. We emulated this behavior in synthetic hydrogels by incorporating trace lipid concentrations to create a molecularly thin, lipid-based boundary layer that renews continuously. We observed a 80% to 99.3% reduction in friction and wear relative to the lipid-free gel, over a wide range of conditions. This effect persists when the gels are dried and then rehydrated. Our approach may provide a method for sustained, extreme lubrication of hydrogels in applications from tissue engineering to clinical diagnostics. [1]: /lookup/doi/10.1126/science.aay8276 [2]: /lookup/doi/10.1126/science.abd3831
领域	气候变化 ; 资源环境
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引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/299343
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Weifeng Lin,Monika Kluzek,Noa Iuster,et al. Cartilage-inspired, lipid-based boundary-lubricated hydrogels[J]. Science,2020.
APA	Weifeng Lin.,Monika Kluzek.,Noa Iuster.,Eyal Shimoni.,Nir Kampf.,...&Jacob Klein.(2020).Cartilage-inspired, lipid-based boundary-lubricated hydrogels.Science.
MLA	Weifeng Lin,et al."Cartilage-inspired, lipid-based boundary-lubricated hydrogels".Science (2020).