Microplastic's role in antibiotic resistance

doi:10.1126/science.abd9937

GSTDTAP > 气候变化

DOI	10.1126/science.abd9937
	Microplastic's role in antibiotic resistance
	Michael S. Bank; Yong Sik Ok; Peter W. Swarzenski
	2020-09-11
发表期刊	Science
出版年	2020
英文摘要	Plastic pollution is universal and now viewed as an emerging environmental and human health crisis ([ 1 ][1], [ 2 ][2]). Successful management of plastic waste ([ 3 ][3]) is vital to meeting United Nations Sustainable Development Goal 14, which aims to protect marine ecosystems from pollution and other threats ([ 4 ][4]). Plastic pollution is projected to escalate over the upcoming decades ([ 5 ][5], [ 6 ][6]), but critical knowledge gaps and uncertainties remain about its effects. Evidence that microplastic surfaces in aquatic environments host microorganisms that are resistant to antibiotics ([ 7 ][7], [ 8 ][8]) suggests that plastic pollution could have ramifications on disease transmission and treatment in addition to environmental consequences and human exposure to contaminated air, water, and food. Bacterial biofilms found on microplastics in aquatic ecosystems have been shown to include bacteria with antibiotic-resistant genes ([ 7 ][7], [ 8 ][8]). These resistant bacteria likely originate in human and animal populations treated with antibiotics and then travel downstream through wastewater into riverine and marine ecosystems ([ 9 ][9]). The increasing surface area provided by waste plastics, such as polyethylene, may enable higher rates of biofilm growth, including those containing antibiotic-resistant genes ([ 7 ][7]). The possibility that plastic pollution can facilitate resistance to antibiotics has critical implications for the spread of disease and the management and regulation of antibiotic resistance in the environment ([ 10 ][10]). Although scientists have made important strides in understanding the direct effects of microplastics on animal and plant life ([ 11 ][11]), the indirect effects of plastic pollution, including the sources and transport dynamics of antibiotic resistance, remain unclear. Scientists and policy-makers should prioritize the evaluation of both direct and indirect effects of plastic pollution to fully assess the environmental and public health risks. 1. [↵][12]1. M. S. Bank, 2. S. V. Hansson , Environ. Sci. Technol. 53, 7177 (2019). [OpenUrl][13] 2. [↵][14]1. I. A. Kane et al ., Science 368, 1140 (2020). [OpenUrl][15][Abstract/FREE Full Text][16] 3. [↵][17]1. S. You et al ., Science 368, 1438 (2020). [OpenUrl][18][FREE Full Text][19] 4. [↵][20]United Nations Development Programme, Sustainable Development Goals, Goal 14: Life Below Water ([www.undp.org/content/undp/en/home/sustainable-development-goals/goal-14-life-below-water.html][21]). 5. [↵][22]1. J. R. Jambeck et al ., Science 347, 768 (2015). [OpenUrl][23][Abstract/FREE Full Text][24] 6. [↵][25]1. W. W. Y. Lau et al ., Science, 10.1126/science.aba9475 (2020). 7. [↵][26]1. X.-p. Guo et al ., Sci. Tot. Environ. 745, 140916 (2020). [OpenUrl][27] 8. [↵][28]1. Y. Yang et al ., Appl. Microbiol. Biotechnol. 104, 6501 (2020). [OpenUrl][29] 9. [↵][30]1. S. Berkner et al ., EMBO Rep. 15, 740 (2014). [OpenUrl][31][FREE Full Text][32] 10. [↵][33]1. Y.-G. Zhu, 2. M. Gillings, 3. J. Penuelas , One Earth 3, 23 (2020). [OpenUrl][34] 11. [↵][35]1. S. Anbumani, 2. P. Kakkar , Environ. Sci. Pollut. Res. 25, 14373 (2018). [OpenUrl][36] [1]: #ref-1 [2]: #ref-2 [3]: #ref-3 [4]: #ref-4 [5]: #ref-5 [6]: #ref-6 [7]: #ref-7 [8]: #ref-8 [9]: #ref-9 [10]: #ref-10 [11]: #ref-11 [12]: #xref-ref-1-1 "View reference 1 in text" [13]: {openurl}?query=rft.jtitle%253DEnviron.%2BSci.%2BTechnol.%26rft.volume%253D53%26rft.spage%253D7177%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [14]: #xref-ref-2-1 "View reference 2 in text" [15]: {openurl}?query=rft.jtitle%253DScience%26rft_id%253Dinfo%253Adoi%252F10.1126%252Fscience.aba5899%26rft_id%253Dinfo%253Apmid%252F32354839%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [16]: /lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6Mzoic2NpIjtzOjU6InJlc2lkIjtzOjEzOiIzNjgvNjQ5NS8xMTQwIjtzOjQ6ImF0b20iO3M6MjM6Ii9zY2kvMzY5LzY1MDkvMTMxNS5hdG9tIjt9czo4OiJmcmFnbWVudCI7czowOiIiO30= [17]: #xref-ref-3-1 "View reference 3 in text" [18]: {openurl}?query=rft.jtitle%253DScience%26rft.stitle%253DScience%26rft.aulast%253DYou%26rft.auinit1%253DS.%26rft.volume%253D368%26rft.issue%253D6498%26rft.spage%253D1438%26rft.epage%253D1438%26rft.atitle%253DCOVID-19%2527s%2Bunsustainable%2Bwaste%2Bmanagement%26rft_id%253Dinfo%253Adoi%252F10.1126%252Fscience.abc7778%26rft_id%253Dinfo%253Apmid%252F32587012%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [19]: 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{openurl}?query=rft.jtitle%253DScience%26rft.stitle%253DScience%26rft.aulast%253DJambeck%26rft.auinit1%253DJ.%2BR.%26rft.volume%253D347%26rft.issue%253D6223%26rft.spage%253D768%26rft.epage%253D771%26rft.atitle%253DPlastic%2Bwaste%2Binputs%2Bfrom%2Bland%2Binto%2Bthe%2Bocean%26rft_id%253Dinfo%253Adoi%252F10.1126%252Fscience.1260352%26rft_id%253Dinfo%253Apmid%252F25678662%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [24]: /lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiQUJTVCI7czoxMToiam91cm5hbENvZGUiO3M6Mzoic2NpIjtzOjU6InJlc2lkIjtzOjEyOiIzNDcvNjIyMy83NjgiO3M6NDoiYXRvbSI7czoyMzoiL3NjaS8zNjkvNjUwOS8xMzE1LmF0b20iO31zOjg6ImZyYWdtZW50IjtzOjA6IiI7fQ== [25]: #xref-ref-6-1 "View reference 6 in text" [26]: #xref-ref-7-1 "View reference 7 in text" [27]: {openurl}?query=rft.jtitle%253DSci.%2BTot.%2BEnviron.%26rft.volume%253D745%26rft.spage%253D140916%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [28]: #xref-ref-8-1 "View reference 8 in text" [29]: {openurl}?query=rft.jtitle%253DAppl.%2BMicrobiol.%2BBiotechnol.%26rft.volume%253D104%26rft.spage%253D6501%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [30]: #xref-ref-9-1 "View reference 9 in text" [31]: {openurl}?query=rft.jtitle%253DEMBO%2BRep.%26rft_id%253Dinfo%253Adoi%252F10.15252%252Fembr.201438978%26rft_id%253Dinfo%253Apmid%252F24925529%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [32]: /lookup/ijlink/YTozOntzOjQ6InBhdGgiO3M6MTQ6Ii9sb29rdXAvaWpsaW5rIjtzOjU6InF1ZXJ5IjthOjQ6e3M6ODoibGlua1R5cGUiO3M6NDoiRlVMTCI7czoxMToiam91cm5hbENvZGUiO3M6NToiZW1ib3IiO3M6NToicmVzaWQiO3M6ODoiMTUvNy83NDAiO3M6NDoiYXRvbSI7czoyMzoiL3NjaS8zNjkvNjUwOS8xMzE1LmF0b20iO31zOjg6ImZyYWdtZW50IjtzOjA6IiI7fQ== [33]: #xref-ref-10-1 "View reference 10 in text" [34]: {openurl}?query=rft.jtitle%253DOne%2BEarth%26rft.volume%253D3%26rft.spage%253D23%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [35]: #xref-ref-11-1 "View reference 11 in text" [36]: {openurl}?query=rft.jtitle%253DEnviron.%2BSci.%2BPollut.%2BRes.%26rft.volume%253D25%26rft.spage%253D14373%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx
领域	气候变化 ; 资源环境
URL	查看原文
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/294082
专题	气候变化资源环境科学
推荐引用方式 GB/T 7714	Michael S. Bank,Yong Sik Ok,Peter W. Swarzenski. Microplastic's role in antibiotic resistance[J]. Science,2020.
APA	Michael S. Bank,Yong Sik Ok,&Peter W. Swarzenski.(2020).Microplastic's role in antibiotic resistance.Science.
MLA	Michael S. Bank,et al."Microplastic's role in antibiotic resistance".Science (2020).