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DOI | 10.1016/j.tree.2016.12.008 |
Trait Correlations in the Genomics Era | |
Saltz, Julia B.1; Hessel, Frances C.2; Kelly, Morgan W.3 | |
2017-04-01 | |
发表期刊 | TRENDS IN ECOLOGY & EVOLUTION |
ISSN | 0169-5347 |
EISSN | 1872-8383 |
出版年 | 2017 |
卷号 | 32期号:4 |
文章类型 | Review |
语种 | 英语 |
国家 | USA |
英文摘要 | Thinking about the evolutionary causes and consequences of trait correlations has been dominated by quantitative genetics theory that is focused on hypothetical loci. Since this theory was initially developed, technology has enabled the identification of specific genetic variants that contribute to trait correlations. Here, we review studies of the genetic basis of trait correlations to ask: What has this new information taught us? We find that causal variants can be pleiotropic and/or linked in different ways, indicating that pleiotropy and linkage are not alternative genetic mechanisms. Further, many trait correlations have a polygenic basis, suggesting that both pleiotropy and linkage likely contribute. We discuss implications of these findings for the evolutionary causes and consequences of trait correlations. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000398227300013 |
WOS关键词 | GENOTYPE-PHENOTYPE MAP ; WHITE-THROATED SPARROW ; GENETIC CORRELATIONS ; LOCAL ADAPTATION ; THREESPINE STICKLEBACK ; LINKAGE DISEQUILIBRIUM ; PLEIOTROPIC STRUCTURE ; ARABIDOPSIS-THALIANA ; EVOLUTIONARY BIOLOGY ; COMPLEX ORGANISMS |
WOS类目 | Ecology ; Evolutionary Biology ; Genetics & Heredity |
WOS研究方向 | Environmental Sciences & Ecology ; Evolutionary Biology ; Genetics & Heredity |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/28848 |
专题 | 资源环境科学 |
作者单位 | 1.Rice Univ, 6100 Main St, Houston, TX 77005 USA; 2.Baylor Coll Med, 1 Baylor Plaza, Houston, TX 77030 USA; 3.Louisiana State Univ, 202 Life Sci Bldg, Baton Rouge, LA 70803 USA |
推荐引用方式 GB/T 7714 | Saltz, Julia B.,Hessel, Frances C.,Kelly, Morgan W.. Trait Correlations in the Genomics Era[J]. TRENDS IN ECOLOGY & EVOLUTION,2017,32(4). |
APA | Saltz, Julia B.,Hessel, Frances C.,&Kelly, Morgan W..(2017).Trait Correlations in the Genomics Era.TRENDS IN ECOLOGY & EVOLUTION,32(4). |
MLA | Saltz, Julia B.,et al."Trait Correlations in the Genomics Era".TRENDS IN ECOLOGY & EVOLUTION 32.4(2017). |
条目包含的文件 | 条目无相关文件。 |
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