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DOI | 10.1038/s41586-020-2169-0 |
Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins | |
Li, Jia1; Yang, Xiangdong1; Liu, Yang2; Huang, Bolong3; Wu, Ruixia1; Zhang, Zhengwei1; Zhao, Bei1; Ma, Huifang1; Dang, Weiqi1; Wei, Zheng4; Wang, Kai5; Lin, Zhaoyang2; Yan, Xingxu6; Sun, Mingzi3; Li, Bo1,7; Pan, Xiaoqing6,8; Luo, Jun5; Zhang, Guangyu4; Liu, Yuan1,7; Huang, Yu9; Duan, Xidong1; Duan, Xiangfeng2 | |
2020-03-11 | |
发表期刊 | NATURE |
ISSN | 0028-0836 |
EISSN | 1476-4687 |
出版年 | 2020 |
卷号 | 583期号:7815页码:282-+ |
文章类型 | Article |
语种 | 英语 |
国家 | Peoples R China; Australia |
英文关键词 | The ongoing outbreak of viral pneumonia in China and across the world is associated with a new coronavirus, SARS-CoV-2(1). This outbreak has been tentatively associated with a seafood market in Wuhan, China, where the sale of wild animals may be the source of zoonotic infection(2).Although bats are probable reservoir hosts for SARS-CoV-2, the identity of any intermediate host that may have facilitated transfer to humans is unknown. Here we report the identification of SARS-CoV-2-related coronaviruses in Malayan pangolins (Manisjavanica) seized in anti-smuggling operations in southern China. Metagenomic sequencing identified pangolin-associated coronaviruses that belong to two sub-lineages of SARS-CoV-2-related coronaviruses, including one that exhibits strong similarity in the receptor-binding domain to SARS-CoV-2. The discovery of multiple lineages of pangolin coronavirus and their similarity to SARS-CoV-2 suggests that pangolins should be considered as possible hosts in the emergence of new coronaviruses and should be removed from wet markets to prevent zoonotic transmission. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000546767100020 |
WOS关键词 | RESPIRATORY SYNDROME CORONAVIRUS ; SARS-CORONAVIRUS ; GENOMIC CHARACTERIZATION ; BATS ; ORIGIN ; BETACORONAVIRUSES ; DIVERSITY ; CHINA ; ALPHACORONAVIRUSES ; IDENTIFICATION |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/281217 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Hunan Key Lab Two Dimens Mat, Changsha, Peoples R China; 2.Univ Calif Los Angeles, Dept Chem & Biochem, 405 Hilgard Ave, Los Angeles, CA 90024 USA; 3.Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China; 4.Chinese Acad Sci, Inst Phys, Beijing Natl Lab Condensed Matter Phys, Beijing, Peoples R China; 5.Tianjin Univ Technol, Tianjin Key Lab Adv Funct Porous Mat, Ctr Electron Microscopy, Inst New Energy,Sch Mat, Tianjin, Peoples R China; 6.Univ Calif Irvine, Dept Mat Sci & Engn, Irvine, CA USA; 7.Hunan Univ, Sch Phys & Elect, Changsha, Peoples R China; 8.Univ Calif Irvine, Dept Phys & Astron, Irvine, CA USA; 9.Univ Calif Los Angeles, Dept Mat Sci & Engn, Los Angeles, CA 90024 USA |
推荐引用方式 GB/T 7714 | Li, Jia,Yang, Xiangdong,Liu, Yang,et al. Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins[J]. NATURE,2020,583(7815):282-+. |
APA | Li, Jia.,Yang, Xiangdong.,Liu, Yang.,Huang, Bolong.,Wu, Ruixia.,...&Duan, Xiangfeng.(2020).Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins.NATURE,583(7815),282-+. |
MLA | Li, Jia,et al."Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins".NATURE 583.7815(2020):282-+. |
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