Go to Development of an OECD Guidance Document for the Application of OECD Test Guideline 236 (Acute Fish Embryo Toxicity Test)

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	Go to Development of an OECD Guidance Document for the Application of OECD Test Guideline 236 (Acute Fish Embryo Toxicity Test)
	admin
	2020-06-01
出版年	2020
国家	德国
领域	气候变化
英文摘要	The project goal was to support the regulatory acceptance of data generated with the OECD Acute Fish Embryo Toxicity Test (TG 236) as alternative method to the OECD Acute Fish Toxicity Test (TG 203). TG 236 is an important contribution to animal welfare in chemical safety assessment in Europe but also worldwide. Results of the project are directly used within OECD project 2.54 on the Development of a Guidance Document for an Integrated Approach to Testing and Assessment of Acute Fish Toxicity. Specific results: (1) the knowledge on xenobiotic transformation capacities in zebrafish embryos, juveniles and adults is fragmentary. Therefore, transfer of biotransformation data from juvenile fish to adult fish does not appear justified. (2) The chorion is no barrier for uncharged industrial chemicals of a molecular size of 3,000 – 4,000 Da.
URL	查看原文
来源平台	Federal Environment Agency
文献类型	科技报告
条目标识符	http://119.78.100.173/C666/handle/2XK7JSWQ/276812
专题	气候变化
推荐引用方式 GB/T 7714	admin. Go to Development of an OECD Guidance Document for the Application of OECD Test Guideline 236 (Acute Fish Embryo Toxicity Test),2020.