Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1038/s41467-020-14636-y |
Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda | |
Kate Grabowski, Mary1,2,3; Lessler, Justin2; Bazaale, Jeremiah3; Nabukalu, Dorean3; Nankinga, Justine3; Nantume, Betty3; Ssekasanvu, Joseph2; Reynolds, Steven J.3,4,5; Ssekubugu, Robert3; Nalugoda, Fred3; Kigozi, Godfrey3; Kagaayi, Joseph3; Santelli, John S.6; Kennedy, Caitlin7; Wawer, Maria J.2,3; Serwadda, David3,8; Chang, Larry W.2,3,7; Gray, Ronald H.2,3 | |
2020-02-20 | |
发表期刊 | NATURE COMMUNICATIONS |
ISSN | 2041-1723 |
出版年 | 2020 |
卷号 | 11期号:1 |
文章类型 | Article |
语种 | 英语 |
国家 | USA; Uganda |
英文摘要 | HIV prevalence varies markedly throughout Africa, and it is often presumed areas of higher HIV prevalence (i.e., hotspots) serve as sources of infection to neighboring areas of lower prevalence. However, the small-scale geography of migration networks and movement of HIV-positive individuals between communities is poorly understood. Here, we use population-based data from similar to 22,000 persons of known HIV status to characterize migratory patterns and their relationship to HIV among 38 communities in Rakai, Uganda with HIV prevalence ranging from 9 to 43%. We find that migrants moving into hotspots had significantly higher HIV prevalence than migrants moving elsewhere, but out-migration from hotspots was geographically dispersed, contributing minimally to HIV burden in destination locations. Our results challenge the assumption that high prevalence hotspots are drivers of transmission in regional epidemics, instead suggesting that migrants with high HIV prevalence, particularly women, selectively migrate to these areas. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000517260700009 |
WOS关键词 | ANTIRETROVIRAL THERAPY ; FEMALE MIGRANTS ; SOUTH-AFRICA ; RISK-FACTORS ; TRANSMISSION ; PREVENTION ; DISEASE ; HEALTH ; DETERMINANTS ; ASSOCIATION |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/249796 |
专题 | 资源环境科学 |
作者单位 | 1.Johns Hopkins Sch Med, Dept Pathol, Baltimore, MD 21287 USA; 2.Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, 627 North Washington St, Baltimore, MD 21205 USA; 3.Rakai Hlth Sci Program, Old Bukoba Rd,POB 279, Kalisizo, Uganda; 4.NIAID, Lab Immunoregulat, Div Intramural Res, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA; 5.Johns Hopkins Sch Med, Div Infect Dis, Dept Med, Baltimore, MD 21205 USA; 6.Columbia Univ, Heilbrunn Dept Populat & Family Hlth, 60 Haven Ave, New York, NY 10032 USA; 7.Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, 615 N Wolfe St, Baltimore, MD 21205 USA; 8.Makerere Univ, Sch Publ Hlth, Kampala, Uganda |
推荐引用方式 GB/T 7714 | Kate Grabowski, Mary,Lessler, Justin,Bazaale, Jeremiah,et al. Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda[J]. NATURE COMMUNICATIONS,2020,11(1). |
APA | Kate Grabowski, Mary.,Lessler, Justin.,Bazaale, Jeremiah.,Nabukalu, Dorean.,Nankinga, Justine.,...&Gray, Ronald H..(2020).Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda.NATURE COMMUNICATIONS,11(1). |
MLA | Kate Grabowski, Mary,et al."Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda".NATURE COMMUNICATIONS 11.1(2020). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论