Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1073/pnas.2002268117 |
Honey bee virus causes context-dependent changes in host social behavior | |
Geffre, Amy C.1,9; Gernat, Tim2,3; Harwood, Gyan P.4; Jones, Beryl M.5; Gysi, Deisy Morselli3,10; Hamilton, Adam R.2; Bonning, Bryony C.6; Toth, Amy L.1,7; Robinson, Gene E.2,4,8; Dolezal, Adam G.4 | |
2020-04-27 | |
发表期刊 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA |
ISSN | 0027-8424 |
出版年 | 2020 |
卷号 | 117期号:19页码:10406-10413 |
文章类型 | Article |
语种 | 英语 |
国家 | USA; Germany |
英文摘要 | Anthropogenic changes create evolutionarily novel environments that present opportunities for emerging diseases, potentially changing the balance between host and pathogen. Honey bees provide essential pollination services, but intensification and globalization of honey bee management has coincided with increased pathogen pressure, primarily due to a parasitic mite/ virus complex. Here, we investigated how honey bee individual and group phenotypes are altered by a virus of concern, Israeli acute paralysis virus (IAPV). Using automated and manual behavioral monitoring of IAPV-inoculated individuals, we find evidence for pathogen manipulation of worker behavior by IAPV, and reveal that this effect depends on social context; that is, within versus between colony interactions. Experimental inoculation reduced social contacts between honey bee colony members, suggesting an adaptive host social immune response to diminish transmission. Parallel analyses with double-stranded RNA (dsRNA)-immunostimulated bees revealed these behaviors are part of a generalized social immune defensive response. Conversely, inoculated bees presented to groups of bees from other colonies experienced reduced aggression compared with dsRNA-immunostimulated bees, facilitating entry into susceptible colonies. This reduction was associated with a shift in cuticular hydrocarbons, the chemical signatures used by bees to discriminate colony members from intruders. These responses were specific to IAPV infection, suggestive of pathogen manipulation of the host. Emerging bee pathogens may thus shape host phenotypes to increase transmission, a strategy especiallywellsuited to the unnaturally high colony densities of modern apiculture. These findings demonstrate how anthropogenic changes could affect arms races between human-managed hosts and their pathogens to potentially affect global food security. |
英文关键词 | honey bee virus host-pathogen evolution pathogen manipulation |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000532837500041 |
WOS关键词 | NESTMATE RECOGNITION ; VARROA-DESTRUCTOR ; TRANSMISSION ; COLONIES ; POPULATION ; MECHANISMS ; EMERGENCE ; EVOLUTION |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/249714 |
专题 | 资源环境科学 |
作者单位 | 1.Iowa State Univ, Dept Ecol Evolut & Organismal Biol, Ames, IA 50011 USA; 2.Univ Illinois, Carl R Woese Inst Genom Biol, Urbana, IL 61801 USA; 3.Univ Leipzig, Dept Comp Sci, Fac Math & Comp Sci, D-04109 Leipzig, Germany; 4.Univ Illinois Urbana Campaign, Dept Entomol, Urbana, IL 61801 USA; 5.Univ Illinois, Program Ecol Evolut & Conservat Biol, Urbana, IL 61801 USA; 6.Univ Florida, Dept Entomol & Nematol, Gainesville, FL 32611 USA; 7.Iowa State Univ, Dept Entomol, Ames, IA 50011 USA; 8.Univ Illinois, Neurosci Program, Urbana, IL 61801 USA; 9.Univ Calif San Diego, Div Biol Sci, Sect Ecol Behav & Evolut, San Diego, CA 92093 USA; 10.Northeastern Univ, Ctr Complex Network Res, Boston, MA 02115 USA |
推荐引用方式 GB/T 7714 | Geffre, Amy C.,Gernat, Tim,Harwood, Gyan P.,et al. Honey bee virus causes context-dependent changes in host social behavior[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2020,117(19):10406-10413. |
APA | Geffre, Amy C..,Gernat, Tim.,Harwood, Gyan P..,Jones, Beryl M..,Gysi, Deisy Morselli.,...&Dolezal, Adam G..(2020).Honey bee virus causes context-dependent changes in host social behavior.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,117(19),10406-10413. |
MLA | Geffre, Amy C.,et al."Honey bee virus causes context-dependent changes in host social behavior".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117.19(2020):10406-10413. |
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