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DOI | 10.1038/s41558-019-0687-2 |
Intergenerational epigenetic inheritance in reef-building corals | |
Liew, Yi Jin1,4; Howells, Emily J.2,3,5; Wang, Xin1,6; Michell, Craig T.1,7; Burt, John A.2,3; Idaghdour, Youssef2,3; Aranda, Manuel1 | |
2020-02-10 | |
发表期刊 | NATURE CLIMATE CHANGE
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ISSN | 1758-678X |
EISSN | 1758-6798 |
出版年 | 2020 |
卷号 | 10期号:3页码:254-+ |
文章类型 | Article |
语种 | 英语 |
国家 | Saudi Arabia; U Arab Emirates; Australia; USA; Finland |
英文摘要 | The perception that the inheritance of phenotypic traits operates solely through genetic means is slowly being eroded: epigenetic mechanisms have been shown to induce heritable changes in gene activity in plants(1,2) and metazoans(1,3). Inheritance of DNA methylation patterns provides a potential pathway for environmentally induced phenotypes to contribute to evolution of species and populations(1-5). However, in basal metazoans, it is unknown whether inheritance of CpG methylation patterns occurs across the genome (as in plants) or as rare exceptions (as in mammals)(4). Here, we show that DNA methylation patterns in a reef-building coral are determined by genotype and developmental stage, as well as by parental environment. Transmission of CpG methylation from adults to their sperm and larvae demonstrates genome-wide inheritance. Variation in the hypermethylation of genes in adults and their sperm from distinct environments suggests intergenerational acclimatization to local temperature and salinity. Furthermore, genotype-independent adjustments of methylation levels in stress-related genes were strongly correlated with offspring survival rates under heat stress. These findings support a role of DNA methylation in the intergenerational inheritance of traits in corals, which could extend to enhancing their capacity to adapt to climate change. Intergenerational inheritance of traits in corals can help species survive environmental change. Examination of intergenerational DNA methylation profiles in a reef-building coral shows there to be genome-wide inheritance, with the potential for adaptive capacity to environmental stressors. |
领域 | 资源环境 |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000512529500002 |
WOS关键词 | FALSE DISCOVERY RATE ; DNA METHYLATION ; THERMAL-STRESS ; HOST ; MECHANISMS ; SYMBIONT ; IMPACT ; MEMORY |
WOS类目 | Environmental Sciences ; Environmental Studies ; Meteorology & Atmospheric Sciences |
WOS研究方向 | Environmental Sciences & Ecology ; Meteorology & Atmospheric Sciences |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/249505 |
专题 | 资源环境科学 |
作者单位 | 1.King Abdullah Univ Sci & Technol, Red Sea Res Ctr, Biol & Environm Sci & Engn Div, Thuwal, Saudi Arabia; 2.New York Univ Abu Dhabi, Ctr Genom & Syst Biol, Abu Dhabi, U Arab Emirates; 3.New York Univ Abu Dhabi, Program Biol, Abu Dhabi, U Arab Emirates; 4.CSIRO Hlth & Biosecur, N Ryde, NSW, Australia; 5.Univ Wollongong, Ctr Sustainable Ecosyst Solut, Sch Earth Atmospher & Life Sci, Wollongong, NSW, Australia; 6.Houston Methodist, Ctr Cardiovasc Regenerat, Houston, TX USA; 7.Univ Eastern Finland, Dept Environm & Biol Sci, Joensuu, Finland |
推荐引用方式 GB/T 7714 | Liew, Yi Jin,Howells, Emily J.,Wang, Xin,et al. Intergenerational epigenetic inheritance in reef-building corals[J]. NATURE CLIMATE CHANGE,2020,10(3):254-+. |
APA | Liew, Yi Jin.,Howells, Emily J..,Wang, Xin.,Michell, Craig T..,Burt, John A..,...&Aranda, Manuel.(2020).Intergenerational epigenetic inheritance in reef-building corals.NATURE CLIMATE CHANGE,10(3),254-+. |
MLA | Liew, Yi Jin,et al."Intergenerational epigenetic inheritance in reef-building corals".NATURE CLIMATE CHANGE 10.3(2020):254-+. |
条目包含的文件 | 条目无相关文件。 |
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