Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP124 |
The Association between Ambient Fine Particulate Air Pollution and Lung Cancer Incidence: Results from the AHSMOG-2 Study | |
Gharibvand, Lida1; Shavlik, David2; Ghamsary, Mark3; Beeson, W. Lawrence1,2; Soret, Samuel3; Knutsen, Raymond1,2; Knutsen, Synnove F.1,2 | |
2017-03-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES
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ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2017 |
卷号 | 125期号:3 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | Background: There is a positive association between ambient fine particulate matter <= 2.5 mu m in aerodynamic diameter (PM2.5) and incidence and mortality of lung cancer (LC), but few studies have assessed the relationship between ambient PM2.5 and LC among never smokers. Objectives: We assessed the association between PM2.5 and risk of LC using the Adventist Health and Smog Study-2 (AHSMOG-2), a cohort of health conscious nonsmokers where 81% have never smoked. Methods: A total of 80,285 AHSMOG-2 participants were followed for an average of 7.5 years with respect to incident LC identified through linkage with U.S. state cancer registries. Estimates of ambient air pollution levels at participants' residences were obtained for 2000 and 2001, the years immediately prior to the start of the study. Results: A total of 250 incident LC cases occurred during 598,927 person-years of follow-up. For each 10-mu g/m(3) increment in PM2.5, adjusted hazard ratio (HR) with 95% confidence interval (CI) for LC incidence was 1.43 (95% CI: 1.11, 1.84) in the two-pollutant multivariable model with ozone. Among those who spent > 1 hr/day outdoors or who had lived 5 or more years at their enrollment address, the HR was 1.68 (95% CI: 1.28, 2.22) and 1.54 (95% CI: 1.17, 2.04), respectively. Conclusion: Increased risk estimates of LC were observed for each 10-mu g/m(3) increment in ambient PM2.5 concentration. The estimate was higher among those with longer residence at enrollment address and those who spent > 1 hr/day outdoors. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000395714400018 |
WOS关键词 | LONG-TERM EXPOSURE ; CIGARETTE-SMOKING ; RISK ; MORTALITY ; COHORT ; PM2.5 ; POLLUTANTS ; COMPONENTS ; HEALTH ; AREAS |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/24191 |
专题 | 资源环境科学 |
作者单位 | 1.Loma Linda Univ, Sch Publ Hlth, Adventist Hlth Study 2, Loma Linda, CA 92350 USA; 2.Loma Linda Univ, Sch Publ Hlth, Ctr Nutr Hlth Lifestyle & Dis Prevent, Loma Linda, CA 92350 USA; 3.Loma Linda Univ, Sch Publ Hlth, Ctr Community Resilience, Loma Linda, CA 92350 USA |
推荐引用方式 GB/T 7714 | Gharibvand, Lida,Shavlik, David,Ghamsary, Mark,et al. The Association between Ambient Fine Particulate Air Pollution and Lung Cancer Incidence: Results from the AHSMOG-2 Study[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2017,125(3). |
APA | Gharibvand, Lida.,Shavlik, David.,Ghamsary, Mark.,Beeson, W. Lawrence.,Soret, Samuel.,...&Knutsen, Synnove F..(2017).The Association between Ambient Fine Particulate Air Pollution and Lung Cancer Incidence: Results from the AHSMOG-2 Study.ENVIRONMENTAL HEALTH PERSPECTIVES,125(3). |
MLA | Gharibvand, Lida,et al."The Association between Ambient Fine Particulate Air Pollution and Lung Cancer Incidence: Results from the AHSMOG-2 Study".ENVIRONMENTAL HEALTH PERSPECTIVES 125.3(2017). |
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