Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP2503 |
Global Estimate of Lung Cancer Mortality Attributable to Residential Radon | |
Gaskin, Janet1; Coyle, Doug1; Whyte, Jeff2; Krewksi, Daniel1 | |
2018-05-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES |
ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2018 |
卷号 | 126期号:5 |
文章类型 | Article |
语种 | 英语 |
国家 | Canada |
英文摘要 | BACKGROUND: Radon is the second most important cause of lung cancer, ranked by the World Health Organization as the fifth leading cause of mortality in 2010. An updated database of national radon exposures for 66 countries allows the global burden of lung cancer mortality attributable to radon to be estimated. OBJECTIVE: Our goal was to estimate the global population attributable burden of lung cancer mortality in 2012 from residential radon. METHODS: Estimates of the population attributable risk (PAR) of lung cancer mortality from radon were determined using the attributable fraction approach, using three models for excess relative risk of lung cancer from radon. RESULTS: The estimates of the median PAR of lung cancer mortality from residential radon in 2012 for the 66 countries having representative national radon surveys were consistent, as 16.5%, 14.4%, and 13.6% for the exposure-age-concentration (EAC) model (BEIR VI), the Hunter model, and the Kreuzer model, respectively. The mean PAR using the EAC model ranged from 4.2% (95% CI: 0.9, 11.7) for Japan, to 29.3% (95% CI: 22.9, 35.7) for Armenia, with a median for the 66 countries of 16.5%. Radon-attributable lung cancer deaths for all 66 countries totaled 226,057 in 2012 and represent a median of 3.0% of total cancer deaths. CONCLUSIONS: Consistent findings between the three models used to estimate excess relative risks of lung cancer from radon, and between the attributable fraction methodology and the life table analysis, confirm that residential radon is responsible for a substantial proportion of lung cancer mortality |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000433628200002 |
WOS关键词 | EXPOSED MINERS ; RISK ; UNCERTAINTY ; POPULATION ; CANADA ; SMOKING ; MODELS |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/22577 |
专题 | 资源环境科学 |
作者单位 | 1.Univ Ottawa, Sch Epidemiol & Publ Hlth, Ottawa, ON, Canada; 2.Hlth Canada, Radiat Protect Bur, Ottawa, ON, Canada |
推荐引用方式 GB/T 7714 | Gaskin, Janet,Coyle, Doug,Whyte, Jeff,et al. Global Estimate of Lung Cancer Mortality Attributable to Residential Radon[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2018,126(5). |
APA | Gaskin, Janet,Coyle, Doug,Whyte, Jeff,&Krewksi, Daniel.(2018).Global Estimate of Lung Cancer Mortality Attributable to Residential Radon.ENVIRONMENTAL HEALTH PERSPECTIVES,126(5). |
MLA | Gaskin, Janet,et al."Global Estimate of Lung Cancer Mortality Attributable to Residential Radon".ENVIRONMENTAL HEALTH PERSPECTIVES 126.5(2018). |
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