Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP5220 |
Long-Term Exposure to Ambient Fine Particulate Matter (PM2.5) and Lung Function in Children, Adolescents, and Young Adults: A Longitudinal Cohort Study | |
Guo, Cui1; Hoek, Gerard2; Chang, Ly-yun3,4; Bo, Yacong1,5; Lin, Changqing6,7; Huang, Bo8; Chan, Ta-chien9; Tam, Tony10; Lau, Alexis K. H.6,7; Lao, Xiang Qian1,11 | |
2019-12-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES |
ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2019 |
卷号 | 127期号:12 |
文章类型 | Article |
语种 | 英语 |
国家 | Peoples R China; Netherlands; Taiwan |
英文摘要 | BACKGROUND: The association between long-term exposure to ambient fine particulate matter with aerodynamic diameter <= 2.5 mu m (PM2.5) and lung function in young people remains uncertain, particularly in Asia, where air pollution is generally a serious problem. OBJECTIVES: This study investigated the association between long-term exposure to ambient PM2.5 and lung function in Taiwanese children, adolescents, and young adults. METHODS: This study comprised 24,544 participants 6-24 years of age, with 33,506 medical observations made between 2000 and 2014. We used a spatiotemporal model to estimate PM2.5 concentrations at participants' addresses. Spirometry parameters, i.e., forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), and maximum midexpiratory flow (IVEVIEF), were determined. A generalized linear mixed model was used to examine the associations between long-term exposure to ambient PM2.5 and lung function. The odds ratios (ORs) of poor lung function were also calculated after adjusting for a range of covariates. RESULTS: Every 10-mu g/m(3) increase in the 2-y average PM2.5 concentration was associated with decreases of 2.22% [95% confidence interval (CI): -2.60, -1.85], 2.94 (95% CI: -3.36, -2.51), and 2.79% (95% CI: -3.15, -2.41) in the FVC, FEV1, and MMEF, respectively. Furthermore, it was associated with a 20% increase in the prevalence of poor lung function (OR: 1.20; 95% CI: 1.12, 1.29). CONCLUSIONS: Two year ambient PM2.5 concentrations were inversely associated with lung function and positively associated with the prevalence of poor lung function in children, adolescents, and young adults in Taiwan. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000505244800009 |
WOS关键词 | AIR-POLLUTION ; ALLERGIC SENSITIZATION ; RESPIRATORY SYMPTOMS ; PARENTAL SMOKING ; OXIDATIVE STRESS ; FUNCTION GROWTH ; ASSOCIATION ; CHINESE ; INFLAMMATION ; IMPAIRMENT |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/224632 |
专题 | 环境与发展全球科技态势 |
作者单位 | 1.Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Peoples R China; 2.Univ Utrecht, Inst Risk Assessment Sci, Utrecht, Netherlands; 3.Acad Sinica, Inst Sociol, Taipei, Taiwan; 4.Gratia Christian Coll, Hong Kong, Peoples R China; 5.Zhengzhou Univ, Sch Publ Hlth, Zhengzhou, Henan, Peoples R China; 6.Hong Kong Univ Sci & Technol, Div Environm & Sustainabil, Hong Kong, Peoples R China; 7.Hong Kong Univ Sci & Technol, Dept Civil & Environm Engn, Hong Kong, Peoples R China; 8.Chinese Univ Hong Kong, Dept Geog & Resource Management, Hong Kong, Peoples R China; 9.Acad Sinica, Res Ctr Humanities & Social Sci, Taipei, Taiwan; 10.Chinese Univ Hong Kong, Dept Sociol, Hong Kong, Peoples R China; 11.Chinese Univ Hong Kong, Shenzhen Res Inst, Shenzhen, Guangdong, Peoples R China |
推荐引用方式 GB/T 7714 | Guo, Cui,Hoek, Gerard,Chang, Ly-yun,et al. Long-Term Exposure to Ambient Fine Particulate Matter (PM2.5) and Lung Function in Children, Adolescents, and Young Adults: A Longitudinal Cohort Study[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2019,127(12). |
APA | Guo, Cui.,Hoek, Gerard.,Chang, Ly-yun.,Bo, Yacong.,Lin, Changqing.,...&Lao, Xiang Qian.(2019).Long-Term Exposure to Ambient Fine Particulate Matter (PM2.5) and Lung Function in Children, Adolescents, and Young Adults: A Longitudinal Cohort Study.ENVIRONMENTAL HEALTH PERSPECTIVES,127(12). |
MLA | Guo, Cui,et al."Long-Term Exposure to Ambient Fine Particulate Matter (PM2.5) and Lung Function in Children, Adolescents, and Young Adults: A Longitudinal Cohort Study".ENVIRONMENTAL HEALTH PERSPECTIVES 127.12(2019). |
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