Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP392 |
Long-Term Exposure to Traffic-Related Air Pollution and Risk of Incident Atrial Fibrillation: A Cohort Study | |
Monrad, Maria1; Sajadieh, Ahmad2; Christensen, Jeppe Schultz1; Ketzel, Matthias3; Raaschou-Nielsen, Ole1,3; Tjonneland, Anne1; Overvad, Kim4; Loft, Steffen5; Sorensen, Mette1 | |
2017-03-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES
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ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2017 |
卷号 | 125期号:3 |
文章类型 | Article |
语种 | 英语 |
国家 | Denmark |
英文摘要 | BACKGROUND: Atrial fibrillation is the most common sustained arrhythmia and is associated with cardiovascular morbidity and mortality. The few studies conducted on short-term effects of air pollution on episodes of atrial fibrillation indicate a positive association, though not consistently. OBJECTIVES: The aim of this study was to evaluate the long-term impact of traffic-related air pollution on incidence of atrial fibrillation in the general population. METHODS: In the Danish Diet, Cancer, and Health cohort of 57,053 people 50-64 years old at enrollment in 1993-1997, we identified 2,700 cases of first-ever hospital admission for atrial fibrillation from enrollment to end of follow-up in 2011. For all cohort members, exposure to traffic-related air pollution assessed as nitrogen dioxide (NO2) and nitrogen oxides (NOx) was estimated at all present and past residential addresses from 1984 to 2011 using a validated dispersion model. We used Cox proportional hazard model to estimate associations between long-term residential exposure to NO2 and NOx and risk of atrial fibrillation, after adjusting for lifestyle and socioeconomic position. RESULTS: A 10 mu g/m(3) higher 10-year time-weighted mean exposure to NO2 preceding diagnosis was associated with an 8% higher risk of atrial fibrillation [incidence rate ratio: 1.08; 95% confidence interval (CI): 1.01, 1.14] in adjusted analysis. Though weaker, similar results were obtained for long-term residential exposure to NOx. We found no clear tendencies regarding effect modification of the association between NO2 and atrial fibrillation by sex, smoking, hypertension or myocardial infarction. CONCLUSION: We found long-term residential traffic-related air pollution to be associated with higher risk of atrial fibrillation. Accordingly, the present findings lend further support to the demand for abatement of air pollution. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000395714400024 |
WOS关键词 | AUTONOMIC NERVOUS-SYSTEM ; PARTICULATE MATTER ; CARDIOVASCULAR-DISEASE ; CONCENTRATED COARSE ; DANISH ; MORTALITY ; PREVALENCE ; STREET ; PARTICLES ; TRENDS |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/22447 |
专题 | 资源环境科学 |
作者单位 | 1.Danish Canc Soc, Diet Genes & Environm, Res Ctr, Strandboulevarden 49, DK-2100 Copenhagen, Denmark; 2.Copenhagen Univ Hosp Bispebjerg, Dept Cardiol, Bispebjerg, Denmark; 3.Aarhus Univ, Dept Environm Sci, Roskilde, Denmark; 4.Aarhus Univ, Epidemiol Sect, Dept Publ Hlth, Aarhus, Denmark; 5.Univ Copenhagen, Fac Hlth & Med Sci, Environm Hlth Sect, Dept Publ Hlth, Copenhagen, Denmark |
推荐引用方式 GB/T 7714 | Monrad, Maria,Sajadieh, Ahmad,Christensen, Jeppe Schultz,et al. Long-Term Exposure to Traffic-Related Air Pollution and Risk of Incident Atrial Fibrillation: A Cohort Study[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2017,125(3). |
APA | Monrad, Maria.,Sajadieh, Ahmad.,Christensen, Jeppe Schultz.,Ketzel, Matthias.,Raaschou-Nielsen, Ole.,...&Sorensen, Mette.(2017).Long-Term Exposure to Traffic-Related Air Pollution and Risk of Incident Atrial Fibrillation: A Cohort Study.ENVIRONMENTAL HEALTH PERSPECTIVES,125(3). |
MLA | Monrad, Maria,et al."Long-Term Exposure to Traffic-Related Air Pollution and Risk of Incident Atrial Fibrillation: A Cohort Study".ENVIRONMENTAL HEALTH PERSPECTIVES 125.3(2017). |
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