Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP1545 |
Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits | |
Abrams, Joseph Y.1; Weber, Rodney J.2; Klein, Mitchel3; Samat, Stefanie E.3; Chang, Howard H.4; Strickland, Matthew J.5; Verma, Vishal6; Fang, Ting2; Bates, Josephine T.7; Mulholland, James A.7; Russell, Armistead G.7; Tolbert, Paige E.3 | |
2017-10-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES
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ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2017 |
卷号 | 125期号:10 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | BACKGROUND: Oxidative potential (OP) has been proposed as a measure of toxicity of ambient particulate matter PM). OBJECTIVES: Our goal was to address an important research gap by using daily OP measurements to conduct population-level analysis of the health effects of measured ambient OP. METHODS: A semi-automated dithiothreitol (DTT) analytical system was used to measure daily average OP (OPDTT) in water-soluble fine PM at a central monitor site in Atlanta, Georgia, over eight sampling periods (a total of 196 d) during June 2012-April 2013. Data on emergency department (ED) visits for selected cardiorespiratory outcomes were obtained for the live-county Atlanta metropolitan area. Poisson log-linear regression models controlling for temporal confounders were used to conduct time-series analyses of the relationship between daily counts of ED visits and either the 3-d moving average (lag 0-2) of OPDTT or same-day OPDTT. Bipollutant regression models were run to estimate the health associations of OPDTT while controlling for other pollutants. RESULTS: OPDTT was measured for 196 d (mean = 0.32 nmol/min/m(3), interquartile range = 0.21). Lag 0-2 OPDTT was associated with El) visits for respiratory disease (RR = 1.03, 95% confidence interval (CI): 1.00, 1.05 per interquartile range increase in OPDTT), asthma (RR = 1.12, 95% CI: 1.03, 1.22), and ischemic heart disease (RR = 1.19, 95% CI: 1.03, 1.38). Same-day OPDTT was not associated with ED visits for any outcome. Lag 0-2 OPDTT remained a significant predictor of asthma and ischemic heart disease in most bipollutant models. CONCLUSIONS: Lag 0-2 OPDTT was associated with ED visits for multiple cardiorespiratory outcomes, providing support for the utility of OPDTT as a measure of fine particle toxicity. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000413793300020 |
WOS关键词 | EXPOSURE MEASUREMENT ERROR ; WATER-SOLUBLE PM2.5 ; SOUTHEASTERN AEROSOL RESEARCH ; SHORT-TERM ASSOCIATIONS ; AIR-POLLUTION ; DIESEL EXHAUST ; TIME-SERIES ; HOSPITAL ADMISSIONS ; RAPTES PROJECT ; RESPIRATORY HEALTH |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/22360 |
专题 | 资源环境科学 |
作者单位 | 1.Emory Univ, Rollins Sch Publ Hlth, Dept Epidemiol, Atlanta, GA 30322 USA; 2.Georgia Inst Technol, Sch Earth & Atmospher Sci, Atlanta, GA 30332 USA; 3.Emory Univ, Rollins Sch Publ Hlth, Dept Environm Hlth, Atlanta, GA 30322 USA; 4.Emory Univ, Rollins Sch Publ Hlth, Dept Biostat, Atlanta, GA 30322 USA; 5.Univ Nevada, Sch Community Hlth Sci, Reno, NV 89557 USA; 6.Univ Illinois, Dept Civil & Environm Engn, Champaign, IL USA; 7.Georgia Inst Technol, Sch Civil & Environm Engn, Atlanta, GA 30332 USA |
推荐引用方式 GB/T 7714 | Abrams, Joseph Y.,Weber, Rodney J.,Klein, Mitchel,et al. Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2017,125(10). |
APA | Abrams, Joseph Y..,Weber, Rodney J..,Klein, Mitchel.,Samat, Stefanie E..,Chang, Howard H..,...&Tolbert, Paige E..(2017).Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits.ENVIRONMENTAL HEALTH PERSPECTIVES,125(10). |
MLA | Abrams, Joseph Y.,et al."Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits".ENVIRONMENTAL HEALTH PERSPECTIVES 125.10(2017). |
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