Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1289/EHP2738 |
Maternal Smoking during Pregnancy and Early Childhood and Development of Asthma and Rhinoconjunctivitis - a MeDALL Project | |
Thacher, Jesse D.1; Gehring, Ulrike2; Gruzieva, Olena1; Standl, Marie3; Pershagen, Goran1,4; Bauer, Carl-Peter5; Berdel, Dietrich6; Keller, Theresa7; Koletzko, Sibylle8; Koppelman, Gerard H.9,10,11; Ku, Inger1,12,13; Lau, Susanne14; Lehmann, Irina15,16; Maier, Dieter17; Schikowski, Tamara18; Wahn, Ulrich14; Wijga, Alet H.19; Heinrich, Joachim3,20; Bousquet, Jean21,22,23; Anto, Josep M.24,25,26,27; von Berg, Andrea6; Melen, Erik1,4,12; Smit, Henriette A.28; Keil, Thomas7; Bergstrom, Anna1,4 | |
2018-04-01 | |
发表期刊 | ENVIRONMENTAL HEALTH PERSPECTIVES
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ISSN | 0091-6765 |
EISSN | 1552-9924 |
出版年 | 2018 |
卷号 | 126期号:4 |
文章类型 | Article |
语种 | 英语 |
国家 | Sweden; Netherlands; Germany; France; Spain |
英文摘要 | BACKGROUND: The role of tobacco smoke exposure in the development and persistence of asthma and rhinoconjunctivitis through childhood into adolescence is unclear. OBJECTIVES: We assessed the associations of parental smoking from fetal life through adolescence with asthma and rhinoconjunctivitis during childhood and adolescence. METHODS: We analyzed data for 10,860 participants of five European birth cohort studies from the Mechanisms of the Development of Allergy (MeDALL) consortium. Parental smoking habits and health outcomes (early transient, persistent, and adolescent-onset asthma and rhinoconjunctivitis) were based on questionnaires covering the period from pregnancy to 14-16 y of age. Data were combined and analyzed using a one-stage and two stage individual participant data meta-analysis. RESULTS: Overall, any maternal smoking during pregnancy tended to be associated with an increased odds of prevalent asthma [adjusted odds ratio (aOR) = 1.19 (95% Cl: 0.98, 1.43)1, but not prevalent rhinoconjunctivitis [aOR = 1.05 (95% Cl: 0.90, 1.22)1, during childhood and adolescence. In analyses with phenotypes related to age of onset and persistence of disease, any maternal smoking during pregnancy was associated with early transient asthma [aOR = 1.79 (95% Cl: 1.14, 2.83)]. :Maternal smoking of >= 10 cigarettes/day during pregnancy was associated with persistent asthma [aOR = 1.66 (95% CI: 1.29, 2.15)] and persistent rhinoconjunctivitis [aOR =1.55 (95% CI, 1.09, 2.20)]. Tobacco smoke exposure during fetal life, infancy, childhood, and adolescence was not associated with adolescent-onset asthma or rhinoconjunctivitis. CONCLUSIONS: Findings from this combined analysis of live European birth cohorts strengthen evidence linking early exposure to tobacco smoke with asthma during childhood and adolescence, Children with high early-life exposure were more likely than unexposed children to have early transient and persistent asthma and persistent rhinoconjunctivitis. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000431396900013 |
WOS关键词 | SOLID FOOD INTRODUCTION ; POSTNATAL EXPOSURE ; PARENTAL REPORTS ; PASSIVE SMOKING ; POOLED ANALYSIS ; BIRTH COHORTS ; TOBACCO-SMOKE ; FOLLOW-UP ; ECZEMA ; AGE |
WOS类目 | Environmental Sciences ; Public, Environmental & Occupational Health ; Toxicology |
WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Toxicology |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/22350 |
专题 | 资源环境科学 |
作者单位 | 1.Karolinska Inst, Inst Environm Med, Box 210, SE-17177 Stockholm, Sweden; 2.Univ Utrecht, IRAS, Utrecht, Netherlands; 3.German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol, Neuherberg, Germany; 4.Stockholm Cty Council, Ctr Occupat & Environm Med, Stockholm, Sweden; 5.Tech Univ Munich, Dept Pediat, Munich, Germany; 6.Marien Hosp Wesel, Res Inst, Dept Paediat, Wesel, Germany; 7.Charite Univ Med Berlin, Inst Social Med Epidemiol & Hlth Econ, Berlin, Germany; 8.Ludwig Maximilians Univ Munchen, Med Ctr, Dr Von Hauner Childrens Hosp, Munich, Germany; 9.Univ Groningen, Univ Med Ctr Groningen, Beatrix Childrens Hosp, Dept Paediat Pulmonol & Paediat Allergol, Groningen, Netherlands; 10.Univ Groningen, Univ Med Ctr Groningen, Groningen Res Inst Asthma, Groningen, Netherlands; 11.Univ Groningen, Univ Med Ctr Groningen, COPD GRIAC, Groningen, Netherlands; 12.Soder Sjukhuset, Sachs Children & Youth Hosp, Stockholm, Sweden; 13.Soder Sjukhuset, Karolinska Inst, Dept Clin Sci & Educ, Stockholm, Sweden; 14.Charite Univ Med Berlin, Div Pneumol & Immunol, Dept Pediat, Berlin, Germany; 15.UFZ Helmholtz Ctr Environm Res, Dept Environm Immunol, Leipzig, Germany; 16.UFZ Helmholtz Ctr Environm Res, Core Facil Studies, Leipzig, Germany; 17.Biomax Informat AG, Munich, Germany; 18.IUF Leibniz Res Inst Environm Med, Dusseldorf, Germany; 19.Natl Inst Publ Hlth & Environm, Ctr Nutr Prevent & Hlth Serv, Bilthoven, Netherlands; 20.Univ Hosp Munich LMU, Inner City Clin, Inst & Outpatient Clin Occupat Social & Environm, Munich, Germany; 21.MACVIA France, Contre Malad Chron Vieillissement Actif France Eu, Montpellier, France; 22.INSERM, U 1168, V1MA Ageing & Chron Dis Epidemiol & Publ Hlth App, Villejuif, France; 23.Univ Versailles St Quentin En Yvelines, UMR S 1168, Montigny Le Bretonneux, France; 24.Ctr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain; 25.Hosp del Mar Med Res Inst IMIM, Barcelona, Spain; 26.CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain; 27.UPF, Barcelona, Spain; 28.Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands |
推荐引用方式 GB/T 7714 | Thacher, Jesse D.,Gehring, Ulrike,Gruzieva, Olena,et al. Maternal Smoking during Pregnancy and Early Childhood and Development of Asthma and Rhinoconjunctivitis - a MeDALL Project[J]. ENVIRONMENTAL HEALTH PERSPECTIVES,2018,126(4). |
APA | Thacher, Jesse D..,Gehring, Ulrike.,Gruzieva, Olena.,Standl, Marie.,Pershagen, Goran.,...&Bergstrom, Anna.(2018).Maternal Smoking during Pregnancy and Early Childhood and Development of Asthma and Rhinoconjunctivitis - a MeDALL Project.ENVIRONMENTAL HEALTH PERSPECTIVES,126(4). |
MLA | Thacher, Jesse D.,et al."Maternal Smoking during Pregnancy and Early Childhood and Development of Asthma and Rhinoconjunctivitis - a MeDALL Project".ENVIRONMENTAL HEALTH PERSPECTIVES 126.4(2018). |
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