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DOI | 10.1038/s41467-019-08849-z |
Large-scale suppression of recombination predates genomic rearrangements in Neurospora tetrasperma | |
Sun, Yu1; Svedberg, Jesper2; Hiltunen, Markus2; Corcoran, Padraic3; Johannesson, Hanna2 | |
2019-02-22 | |
发表期刊 | NATURE COMMUNICATIONS |
ISSN | 2041-1723 |
出版年 | 2017 |
卷号 | 8 |
文章类型 | Article |
语种 | 英语 |
国家 | Peoples R China; Sweden; England |
英文摘要 | A common feature of eukaryote genomes is large chromosomal regions where recombination is absent or strongly reduced, but the factors that cause this reduction are not well understood. Genomic rearrangements have often been implicated, but they may also be a consequence of recombination suppression rather than a cause. In this study, we generate eight high-quality genomic data sets of the filamentous ascomycete Neurospora tetrasperma, a fungus that lacks recombination over most of its largest chromosome. The genomes surprisingly reveal collinearity of the non-recombining regions and although large inversions are enriched in these regions, we conclude these inversions to be derived and not the cause of the suppression. To our knowledge, this is the first time that non-recombining, genic regions as large as 86% of a full chromosome (or 8 Mbp), are shown to be collinear. These findings are of significant interest for our understanding of the evolution of sex chromosomes and other supergene complexes. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000413830800002 |
WOS关键词 | MATING-TYPE CHROMOSOMES ; SEX-CHROMOSOMES ; Y-CHROMOSOME ; EVOLUTION ; INVERSIONS ; HOTSPOTS ; COMPLEX ; HETEROTHALLISM ; METHYLATION ; SUPERGENES |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/204235 |
专题 | 资源环境科学 |
作者单位 | 1.South China Agr Univ, Coll Life Sci, Guangdong Prov Key Lab Prot Funct & Regulat Agr O, Guangzhou 510642, Guangdong, Peoples R China; 2.Uppsala Univ, Dept Organismal Biol, Norbyvagen 18D, S-75236 Uppsala, Sweden; 3.Univ Sheffield, Dept Anim & Plant Sci, Sheffield S10 2TN, S Yorkshire, England |
推荐引用方式 GB/T 7714 | Sun, Yu,Svedberg, Jesper,Hiltunen, Markus,et al. Large-scale suppression of recombination predates genomic rearrangements in Neurospora tetrasperma[J]. NATURE COMMUNICATIONS,2019,8. |
APA | Sun, Yu,Svedberg, Jesper,Hiltunen, Markus,Corcoran, Padraic,&Johannesson, Hanna.(2019).Large-scale suppression of recombination predates genomic rearrangements in Neurospora tetrasperma.NATURE COMMUNICATIONS,8. |
MLA | Sun, Yu,et al."Large-scale suppression of recombination predates genomic rearrangements in Neurospora tetrasperma".NATURE COMMUNICATIONS 8(2019). |
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