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DOI | 10.1038/s41467-018-05156-x |
Streamlined sensory motor communication through cortical reciprocal connectivity in a visually guided eye movement task | |
Itokazu, Takahide1; Hasegawa, Masashi1; Kimura, Rui1; Osaki, Hironobu1,7; Albrecht, Urban-Raphael1; Sohya, Kazuhiro2; Chakrabarti, Shubhodeep1; Itoh, Hideaki3; Ito, Tetsufumi4; Sato, Tatsuo K.1,5; Sato, Takashi R.1,2,6 | |
2018-01-23 | |
发表期刊 | NATURE COMMUNICATIONS |
ISSN | 2041-1723 |
出版年 | 2018 |
卷号 | 9 |
文章类型 | Article |
语种 | 英语 |
国家 | Germany; Japan |
英文摘要 | Cortical computation is distributed across multiple areas of the cortex by networks of reciprocal connectivity. However, how such connectivity contributes to the communication between the connected areas is not clear. In this study, we examine the communication between sensory and motor cortices. We develop an eye movement task in mice and combine it with optogenetic suppression and two-photon calcium imaging techniques. We identify a small region in the secondary motor cortex (MOs) that controls eye movements and reciprocally connects with a rostrolateral part of the higher visual areas (VRL/A/AL). These two regions encode both motor signals and visual information; however, the information flow between the regions depends on the direction of the connectivity: motor information is conveyed preferentially from the MOs to the VRL/A/AL, and sensory information is transferred primarily in the opposite direction. We propose that reciprocal connectivity streamlines information flow, enhancing the computational capacity of a distributed network. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000423057200001 |
WOS关键词 | LONG-RANGE ; FUNCTIONAL SPECIALIZATION ; QUANTITATIVE-ANALYSIS ; PROJECTION NEURONS ; NEURAL SELECTION ; LOCAL CIRCUITS ; BEHAVING MICE ; CORTEX ; FIELD ; RAT |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/203879 |
专题 | 资源环境科学 |
作者单位 | 1.Univ Tubingen, Werner Reichardt Ctr Integrat Neurosci, D-72076 Tubingen, Germany; 2.Natl Ctr Neurol & Psychiat, Natl Inst Neurosci, Dept Mental Disorder Res, Kodaira, Tokyo 1878502, Japan; 3.Saga Univ, Grad Sch Sci & Engn, Saga 8408502, Japan; 4.Kanazawa Med Univ, Dept Anat, Uchinada, Ishikawa 9200293, Japan; 5.Tech Univ Munich, Inst Neurosci, D-80802 Munich, Germany; 6.PRESTO Japan Sci & Technol Agcy, Kawaguchi, Saitama 3320012, Japan; 7.Tokyo Womens Med Univ, Dept Physiol, Tokyo 1628666, Japan |
推荐引用方式 GB/T 7714 | Itokazu, Takahide,Hasegawa, Masashi,Kimura, Rui,et al. Streamlined sensory motor communication through cortical reciprocal connectivity in a visually guided eye movement task[J]. NATURE COMMUNICATIONS,2018,9. |
APA | Itokazu, Takahide.,Hasegawa, Masashi.,Kimura, Rui.,Osaki, Hironobu.,Albrecht, Urban-Raphael.,...&Sato, Takashi R..(2018).Streamlined sensory motor communication through cortical reciprocal connectivity in a visually guided eye movement task.NATURE COMMUNICATIONS,9. |
MLA | Itokazu, Takahide,et al."Streamlined sensory motor communication through cortical reciprocal connectivity in a visually guided eye movement task".NATURE COMMUNICATIONS 9(2018). |
条目包含的文件 | 条目无相关文件。 |
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