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DOI | 10.1038/s41467-017-00557-w |
Human-sized magnetic particle imaging for brain applications | |
Graeser, M.1,2; Thieben, F.1,2; Szwargulski, P.1,2; Werner, F.1,2; Gdaniec, N.1,2; Boberg, M.1,2; Griese, F.1,2; Moeddel, M.1,2; Ludewig, P.3; van de Ven, D.4; Weber, O. M.5; Woywode, O.6; Gleich, B.7; Knopp, T.1,2 | |
2019-04-26 | |
发表期刊 | NATURE COMMUNICATIONS
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ISSN | 2041-1723 |
出版年 | 2019 |
卷号 | 10 |
文章类型 | Article |
语种 | 英语 |
国家 | Germany |
英文摘要 | Determining the brain perfusion is an important task for diagnosis of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis, there is a high risk of restenosis or rebleeding such that patients need intense attention in the days after treatment. Within this work, we present a diagnostic tomographic imager that allows access to brain perfusion quantitatively in short intervals. The device is based on the magnetic particle imaging technology and is designed for human scale. It is highly sensitive and allows the detection of an iron concentration of 263 pmol(Fe) ml(-1), which is one of the lowest iron concentrations imaged by MPI so far. The imager is self-shielded and can be used in unshielded environments such as intensive care units. In combination with the low technical requirements this opens up a variety of medical applications and would allow monitoring of stroke on intensive care units. |
领域 | 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000465837300002 |
WOS关键词 | CONTRAST AGENT ; PERFUSION ; STROKE ; TRACERS ; LIVER |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/203465 |
专题 | 资源环境科学 |
作者单位 | 1.Univ Med Ctr Hamburg Eppendorf, Sect Biomed Imaging, D-20251 Hamburg, Germany; 2.Hamburg Univ Technol, Inst Biomed Imaging, D-21073 Hamburg, Germany; 3.Univ Med Ctr Hamburg Eppendorf, Dept Neurol, D-20251 Hamburg, Germany; 4.Sensing & Inspect Technol GmbH, D-50354 Huerth, Germany; 5.Philips GmbH Market DACH, D-22335 Hamburg, Germany; 6.Philips Med Syst DMC GmbH, Imaging Components, D-22335 Hamburg, Germany; 7.Philips GmbH Innovat Technol, Res Labs, D-22335 Hamburg, Germany |
推荐引用方式 GB/T 7714 | Graeser, M.,Thieben, F.,Szwargulski, P.,et al. Human-sized magnetic particle imaging for brain applications[J]. NATURE COMMUNICATIONS,2019,10. |
APA | Graeser, M..,Thieben, F..,Szwargulski, P..,Werner, F..,Gdaniec, N..,...&Knopp, T..(2019).Human-sized magnetic particle imaging for brain applications.NATURE COMMUNICATIONS,10. |
MLA | Graeser, M.,et al."Human-sized magnetic particle imaging for brain applications".NATURE COMMUNICATIONS 10(2019). |
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