GSTDTAP  > 资源环境科学
DOI10.1038/s41467-017-00557-w
Human-sized magnetic particle imaging for brain applications
Graeser, M.1,2; Thieben, F.1,2; Szwargulski, P.1,2; Werner, F.1,2; Gdaniec, N.1,2; Boberg, M.1,2; Griese, F.1,2; Moeddel, M.1,2; Ludewig, P.3; van de Ven, D.4; Weber, O. M.5; Woywode, O.6; Gleich, B.7; Knopp, T.1,2
2019-04-26
发表期刊NATURE COMMUNICATIONS
ISSN2041-1723
出版年2019
卷号10
文章类型Article
语种英语
国家Germany
英文摘要

Determining the brain perfusion is an important task for diagnosis of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis, there is a high risk of restenosis or rebleeding such that patients need intense attention in the days after treatment. Within this work, we present a diagnostic tomographic imager that allows access to brain perfusion quantitatively in short intervals. The device is based on the magnetic particle imaging technology and is designed for human scale. It is highly sensitive and allows the detection of an iron concentration of 263 pmol(Fe) ml(-1), which is one of the lowest iron concentrations imaged by MPI so far. The imager is self-shielded and can be used in unshielded environments such as intensive care units. In combination with the low technical requirements this opens up a variety of medical applications and would allow monitoring of stroke on intensive care units.


领域资源环境
收录类别SCI-E
WOS记录号WOS:000465837300002
WOS关键词CONTRAST AGENT ; PERFUSION ; STROKE ; TRACERS ; LIVER
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
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文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/203465
专题资源环境科学
作者单位1.Univ Med Ctr Hamburg Eppendorf, Sect Biomed Imaging, D-20251 Hamburg, Germany;
2.Hamburg Univ Technol, Inst Biomed Imaging, D-21073 Hamburg, Germany;
3.Univ Med Ctr Hamburg Eppendorf, Dept Neurol, D-20251 Hamburg, Germany;
4.Sensing & Inspect Technol GmbH, D-50354 Huerth, Germany;
5.Philips GmbH Market DACH, D-22335 Hamburg, Germany;
6.Philips Med Syst DMC GmbH, Imaging Components, D-22335 Hamburg, Germany;
7.Philips GmbH Innovat Technol, Res Labs, D-22335 Hamburg, Germany
推荐引用方式
GB/T 7714
Graeser, M.,Thieben, F.,Szwargulski, P.,et al. Human-sized magnetic particle imaging for brain applications[J]. NATURE COMMUNICATIONS,2019,10.
APA Graeser, M..,Thieben, F..,Szwargulski, P..,Werner, F..,Gdaniec, N..,...&Knopp, T..(2019).Human-sized magnetic particle imaging for brain applications.NATURE COMMUNICATIONS,10.
MLA Graeser, M.,et al."Human-sized magnetic particle imaging for brain applications".NATURE COMMUNICATIONS 10(2019).
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