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The concept of topological phases is a powerful framework for characterizing ground states of quantum many-body systems that goes beyond the paradigm of symmetry breaking. Topological phases can appear in condensed-matter systems naturally, whereas the implementation and study of such quantum many-body ground states in artificial matter require careful engineering. Here, we report the experimental realization of a symmetry-protected topological phase of interacting bosons in a one-dimensional lattice and demonstrate a robust ground state degeneracy attributed to protected zero-energy edge states. The experimental setup is based on atoms trapped in an array of optical tweezers and excited into Rydberg levels, which gives rise to hard-core bosons with an effective hopping generated by dipolar exchange interaction.