Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aax1030 |
Hippocampal sharp-wave ripples linked to visual episodic recollection in humans | |
Norman, Yitzhak1; Yeagle, Erin M.2,3; Khuvis, Simon2,3; Harel, Michal1; Mehta, Ashesh D.2,3; Malach, Rafael1 | |
2019-08-16 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2019 |
卷号 | 365期号:6454页码:657-+ |
文章类型 | Article |
语种 | 英语 |
国家 | Israel; USA |
英文摘要 | Hippocampal sharp-wave ripples (SWRs) constitute one of the most synchronized activation events in the brain and play a critical role in offline memory consolidation. Yet their cognitive content and function during awake, conscious behavior remains unclear. We directly examined this question using intracranial recordings in human patients engaged in episodic free recall of previously viewed photographs. Our results reveal a content-selective increase in hippocampal ripple rate emerging 1 to 2 seconds prior to recall events. During recollection, high-order visual areas showed pronounced SWR-coupled reemergence of activation patterns associated with recalled content. Finally, the SWR rate during encoding predicted subsequent free-recall performance. These results point to a role for hippocampal SWRs in triggering spontaneous recollections and orchestrating the reinstatement of cortical representations during free episodic memory retrieval. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000481688700038 |
WOS关键词 | HIGH-FREQUENCY OSCILLATIONS ; MEDIAL TEMPORAL-LOBE ; HUMAN CEREBRAL-CORTEX ; SLOW OSCILLATIONS ; AWAKE REPLAY ; MEMORY ; SPINDLES ; PATTERNS ; EEG ; NEOCORTEX |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/202089 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Weizmann Inst Sci, Dept Neurobiol, IL-76100 Rehovot, Israel; 2.Donald & Barbara Zucker Sch Med Hofstra Northwell, Dept Neurosurg, Manhasset, NY 11030 USA; 3.Feinstein Inst Med Res, Manhasset, NY 11030 USA |
推荐引用方式 GB/T 7714 | Norman, Yitzhak,Yeagle, Erin M.,Khuvis, Simon,et al. Hippocampal sharp-wave ripples linked to visual episodic recollection in humans[J]. SCIENCE,2019,365(6454):657-+. |
APA | Norman, Yitzhak,Yeagle, Erin M.,Khuvis, Simon,Harel, Michal,Mehta, Ashesh D.,&Malach, Rafael.(2019).Hippocampal sharp-wave ripples linked to visual episodic recollection in humans.SCIENCE,365(6454),657-+. |
MLA | Norman, Yitzhak,et al."Hippocampal sharp-wave ripples linked to visual episodic recollection in humans".SCIENCE 365.6454(2019):657-+. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论