GSTDTAP  > 地球科学
DOI10.1126/science.aax6498
Response to Comment on "Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality"
Mina, Michael J.1,2; Grenfell, Bryan T.3,4; Metcalf, C. Jessica E.3
2019-07-12
发表期刊SCIENCE
ISSN0036-8075
EISSN1095-9203
出版年2019
卷号365期号:6449
文章类型Editorial Material
语种英语
国家USA
英文摘要

Thakkar and McCarthy suggest that periodicity in measles incidence artifactually drives our estimates of a 2- to 3-year duration of measles "immune-amnesia." We show that periodicity has a negligible effect relative to the immunological signal we detect, and demonstrate that immune-amnesia is largely undetectable in small populations with large fluctuations in mortality of the type they use for illustration.


领域地球科学 ; 气候变化 ; 资源环境
收录类别SCI-E ; SSCI
WOS记录号WOS:000474905400002
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
引用统计
文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/201830
专题地球科学
资源环境科学
气候变化
作者单位1.Harvard Sch Publ Hlth, Dept Epidemiol, Ctr Communicable Dis Dynam, Boston, MA 02115 USA;
2.Harvard Med Sch, Dept Pathol, Boston, MA 02115 USA;
3.Princeton Univ, Dept Ecol & Evolutionary Biol, Princeton, NJ 08544 USA;
4.NIH, Fogarty Int Ctr, Bldg 10, Bethesda, MD 20892 USA
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Mina, Michael J.,Grenfell, Bryan T.,Metcalf, C. Jessica E.. Response to Comment on "Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality"[J]. SCIENCE,2019,365(6449).
APA Mina, Michael J.,Grenfell, Bryan T.,&Metcalf, C. Jessica E..(2019).Response to Comment on "Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality".SCIENCE,365(6449).
MLA Mina, Michael J.,et al."Response to Comment on "Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality"".SCIENCE 365.6449(2019).
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