GSTDTAP  > 地球科学
DOI10.1126/science.aau6299
Measles and the canonical path to elimination
Graham, Matthew1; Winter, Amy K.1; Ferrari, Matthew2; Grenfell, Bryan3,4; Moss, William J.1; Azman, Andrew S.1; Metcalf, C. Jessica E.3; Lessler, Justin1
2019-05-10
发表期刊SCIENCE
ISSN0036-8075
EISSN1095-9203
出版年2019
卷号364期号:6440页码:584-+
文章类型Article
语种英语
国家USA
英文摘要

All World Health Organization regions have set measles elimination goals. We find that as countries progress toward these goals, they undergo predictable changes in the size and frequency of measles outbreaks. A country's position on this "canonical path" is driven by both measles control activities and demographic factors, which combine to change the effective size of the measles-susceptible population, thereby driving the country through theoretically established dynamic regimes. Further, position on the path to elimination provides critical information for guiding vaccination efforts, such as the age profile of susceptibility, that could only otherwise be obtained through costly field studies or sophisticated analysis. Equipped with this information, countries can gain insight into their current and future measles epidemiology and select appropriate strategies to more quickly achieve elimination goals.


领域地球科学 ; 气候变化 ; 资源环境
收录类别SCI-E
WOS记录号WOS:000467631800042
WOS关键词CRITICAL COMMUNITY SIZE ; DYNAMICS ; VACCINATION ; EPIDEMICS
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
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文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/201401
专题地球科学
资源环境科学
气候变化
作者单位1.Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA;
2.Penn State Univ, Dept Biol, University Pk, PA 16802 USA;
3.Princeton Univ, Dept Ecol & Evolutionary Biol, Princeton, NJ 08544 USA;
4.NIH, Fogarty Int Ctr, Bldg 10, Bethesda, MD 20892 USA
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GB/T 7714
Graham, Matthew,Winter, Amy K.,Ferrari, Matthew,et al. Measles and the canonical path to elimination[J]. SCIENCE,2019,364(6440):584-+.
APA Graham, Matthew.,Winter, Amy K..,Ferrari, Matthew.,Grenfell, Bryan.,Moss, William J..,...&Lessler, Justin.(2019).Measles and the canonical path to elimination.SCIENCE,364(6440),584-+.
MLA Graham, Matthew,et al."Measles and the canonical path to elimination".SCIENCE 364.6440(2019):584-+.
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