Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aav6428 |
Defining the developmental program leading to meiosis in maize | |
Nelms, Brad; Walbot, Virginia | |
2019-04-05 | |
发表期刊 | SCIENCE
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ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2019 |
卷号 | 364期号:6435页码:52-+ |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | In multicellular organisms, the entry into meiosis is a complex process characterized by increasing meiotic specialization. Using single-cell RNA sequencing, we reconstructed the developmental program into maize male meiosis. A smooth continuum of expression stages before meiosis was followed by a two-step transcriptome reorganization in leptotene, during which 26.7% of transcripts changed in abundance by twofold or more. Analysis of cell-cycle gene expression indicated that nearly all pregerminal cells proliferate, eliminating a stem-cell model to generate meiotic cells. Mutants defective in somatic differentiation or meiotic commitment expressed transcripts normally present in early meiosis after a delay; thus, the germinal transcriptional program is cell autonomous and can proceed despite meiotic failure. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000463585700031 |
WOS关键词 | CELL ; ARABIDOPSIS ; TRANSCRIPTOMES ; IMAGE |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/201129 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | Stanford Univ, Dept Biol, Stanford, CA 94305 USA |
推荐引用方式 GB/T 7714 | Nelms, Brad,Walbot, Virginia. Defining the developmental program leading to meiosis in maize[J]. SCIENCE,2019,364(6435):52-+. |
APA | Nelms, Brad,&Walbot, Virginia.(2019).Defining the developmental program leading to meiosis in maize.SCIENCE,364(6435),52-+. |
MLA | Nelms, Brad,et al."Defining the developmental program leading to meiosis in maize".SCIENCE 364.6435(2019):52-+. |
条目包含的文件 | 条目无相关文件。 |
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