Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aat7164 |
Transmission modes of the mammalian gut microbiota | |
Moeller, Andrew H.1,2,3,5; Suzuki, Taichi A.2,3; Phifer-Rixey, Megan2,3,4; Nachman, Michael W.2,3 | |
2018-10-26 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2018 |
卷号 | 362期号:6413页码:453-456 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | Mammals house a diversity of bacteria that affect health in various ways, but the routes by which bacterial lineages are transmitted between hosts remain poorly understood. We experimentally determined microbiota transmission modes by deriving 17 inbred mouse lines from two wild populations and monitoring their gut microbiotas for up to 11 host generations. Individual-and population-level microbiota compositions were maintained within mouse lines throughout the experiment, indicating predominantly vertical inheritance of the microbiota. However, certain bacterial taxa tended to be exchanged horizontally between mouse lines. Consistent with evolutionary theory, the degree of horizontal transmission predicted bacterial genera with pathogenic representatives responsible for human infections and hospitalizations. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000450441900049 |
WOS关键词 | PATHOGENS ; VIRULENCE ; EVOLUTION ; DISEASE ; SHAPES ; HEALTH |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/199926 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Univ Calif Berkeley, Miller Inst Basic Res Sci, Berkeley, CA 94720 USA; 2.Univ Calif Berkeley, Museum Vertebrate Zool, Berkeley, CA 94720 USA; 3.Univ Calif Berkeley, Dept Integrat Biol, Berkeley, CA 94720 USA; 4.Monmouth Univ, Dept Biol, West Long Branch, NJ 07764 USA; 5.Cornell Univ, Dept Ecol & Evolutionary Biol, New York, NY 14853 USA |
推荐引用方式 GB/T 7714 | Moeller, Andrew H.,Suzuki, Taichi A.,Phifer-Rixey, Megan,et al. Transmission modes of the mammalian gut microbiota[J]. SCIENCE,2018,362(6413):453-456. |
APA | Moeller, Andrew H.,Suzuki, Taichi A.,Phifer-Rixey, Megan,&Nachman, Michael W..(2018).Transmission modes of the mammalian gut microbiota.SCIENCE,362(6413),453-456. |
MLA | Moeller, Andrew H.,et al."Transmission modes of the mammalian gut microbiota".SCIENCE 362.6413(2018):453-456. |
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