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DOI | 10.1126/science.aat4346 |
Single-particle cryo-EM-How did it get here and where will it go | |
Cheng, Yifan | |
2018-08-31 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2018 |
卷号 | 361期号:6405页码:876-+ |
文章类型 | Review |
语种 | 英语 |
国家 | USA |
英文摘要 | Cryo-electron microscopy, or simply cryo-EM, refers mainly to three very different yet closely related techniques: electron crystallography, single-particle cryo-EM, and electron cryotomography. In the past few years, single-particle cryo-EM in particular has triggered a revolution in structural biology and has become a newly dominant discipline. This Review examines the fascinating story of its start and evolution over the past 40-plus years, delves into how and why the recent technological advances have been so groundbreaking, and briefly considers where the technique may be headed in the future. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000443547000028 |
WOS关键词 | BEAM-INDUCED MOTION ; CRYOELECTRON MICROSCOPY ; ELECTRON-MICROSCOPY ; TRP CHANNELS ; ION-CHANNEL ; 3-DIMENSIONAL RECONSTRUCTION ; STRUCTURAL BIOLOGY ; RIBOSOMAL-SUBUNIT ; PROTEIN CRYSTALS ; CRYSTALLOGRAPHY |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/199481 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | Univ Calif San Francisco, Dept Biochem & Biophys, Howard Hughes Med Inst, San Francisco, CA 94143 USA |
推荐引用方式 GB/T 7714 | Cheng, Yifan. Single-particle cryo-EM-How did it get here and where will it go[J]. SCIENCE,2018,361(6405):876-+. |
APA | Cheng, Yifan.(2018).Single-particle cryo-EM-How did it get here and where will it go.SCIENCE,361(6405),876-+. |
MLA | Cheng, Yifan."Single-particle cryo-EM-How did it get here and where will it go".SCIENCE 361.6405(2018):876-+. |
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