GSTDTAP  > 地球科学
DOI10.1126/science.aar8638
HAIRY MERISTEM with WUSCHEL confines CLAVATA3 expression to the outer apical meristem layers
Zhou, Yun1,2,3; Yan, An1,4; Han, Han2,3; Li, Ting1,4; Geng, Yuan2,3; Liu, Xing1,3,5; Meyerowitz, Elliot M.1,4
2018-08-03
发表期刊SCIENCE
ISSN0036-8075
EISSN1095-9203
出版年2018
卷号361期号:6401页码:502-+
文章类型Article
语种英语
国家USA
英文摘要

The control of the location and activity of stem cells depends on spatial regulation of gene activities in the stem cell niche. Using computational and experimental approaches, we have tested and found support for a hypothesis for gene interactions that specify the Arabidopsis apical stem cell population. The hypothesis explains how the WUSCHEL gene product, synthesized basally in the meristem, induces CLAVATA3-expressing stem cells in the meristem apex but, paradoxically, not in the basal domain where WUSCHEL itself is expressed. The answer involves the activity of the small family of HAIRY MERISTEM genes, which prevent the activation of CLAVATA3 and which are expressed basally in the shoot meristem.


领域地球科学 ; 气候变化 ; 资源环境
收录类别SCI-E
WOS记录号WOS:000440627300042
WOS关键词ARABIDOPSIS SHOOT MERISTEMS ; STEM-CELL HOMEOSTASIS ; FLORAL MERISTEMS ; HOMEOBOX GENES ; CLV3 ; MAINTENANCE ; AXILLARY ; FATE ; LOOP
WOS类目Multidisciplinary Sciences
WOS研究方向Science & Technology - Other Topics
引用统计
文献类型期刊论文
条目标识符http://119.78.100.173/C666/handle/2XK7JSWQ/199291
专题地球科学
资源环境科学
气候变化
作者单位1.CALTECH, Div Biol & Biol Engn, Pasadena, CA 91125 USA;
2.Purdue Univ, Dept Bot & Plant Pathol, W Lafayette, IN 47907 USA;
3.Purdue Univ, Purdue Ctr Plant Biol, W Lafayette, IN 47907 USA;
4.CALTECH, Howard Hughes Med Inst, Pasadena, CA 91125 USA;
5.Purdue Univ, Dept Biochem, W Lafayette, IN 47907 USA
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Zhou, Yun,Yan, An,Han, Han,et al. HAIRY MERISTEM with WUSCHEL confines CLAVATA3 expression to the outer apical meristem layers[J]. SCIENCE,2018,361(6401):502-+.
APA Zhou, Yun.,Yan, An.,Han, Han.,Li, Ting.,Geng, Yuan.,...&Meyerowitz, Elliot M..(2018).HAIRY MERISTEM with WUSCHEL confines CLAVATA3 expression to the outer apical meristem layers.SCIENCE,361(6401),502-+.
MLA Zhou, Yun,et al."HAIRY MERISTEM with WUSCHEL confines CLAVATA3 expression to the outer apical meristem layers".SCIENCE 361.6401(2018):502-+.
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