Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aar4142 |
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes | |
Cai, Qiang1; Qiao, Lulu1,2; Wang, Ming1; He, Baoye1; Lin, Feng-Mao3; Palmquist, Jared1; Huang, Sienna-Da3; Jin, Hailing1 | |
2018-06-08 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2018 |
卷号 | 360期号:6393页码:1126-1129 |
文章类型 | Article |
语种 | 英语 |
国家 | USA; Peoples R China; Taiwan |
英文摘要 | Some pathogens and pests deliver small RNAs (sRNAs) into host cells to suppress host immunity. Conversely, hosts also transfer sRNAs into pathogens and pests to inhibit their virulence. Although sRNA trafficking has been observed in a wide variety of interactions, how sRNAs are transferred, especially from hosts to pathogens and pests, is still unknown. Here, we show that host Arabidopsis cells secrete exosome-like extracellular vesicles to deliver sRNAs into fungal pathogen Botrytis cinerea. These sRNA-containing vesicles accumulate at the infection sites and are taken up by the fungal cells. Transferred host sRNAs induce silencing of fungal genes critical for pathogenicity. Thus, Arabidopsis has adapted exosome-mediated cross-kingdom RNA interference as part of its immune responses during the evolutionary arms race with the pathogen. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000434635500048 |
WOS关键词 | MESSENGER-RNAS ; ARABIDOPSIS ; MICRORNAS ; TRAFFICKING ; BIOGENESIS ; RESISTANCE ; EXCHANGE ; DOMAINS ; PATHWAY ; CELLS |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/198844 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Univ Calif Riverside, Inst Integrat Genome Biol, Ctr Plant Cell Biol, Dept Microbiol & Plant Pathol, 900 Univ Ave, Riverside, CA 92521 USA; 2.Nanjing Agr Univ, Dept Plant Protect, Nanjing 210095, Jiangsu, Peoples R China; 3.Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu 300, Taiwan |
推荐引用方式 GB/T 7714 | Cai, Qiang,Qiao, Lulu,Wang, Ming,et al. Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes[J]. SCIENCE,2018,360(6393):1126-1129. |
APA | Cai, Qiang.,Qiao, Lulu.,Wang, Ming.,He, Baoye.,Lin, Feng-Mao.,...&Jin, Hailing.(2018).Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes.SCIENCE,360(6393),1126-1129. |
MLA | Cai, Qiang,et al."Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes".SCIENCE 360.6393(2018):1126-1129. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论