Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aar3684 |
Natural selection interacts with recombination to shape the evolution of hybrid genomes | |
Schumer, Molly1,2,3,4; Xu, Chenling5; Powell, Daniel L.4,6; Durvasula, Arun7; Skov, Laurits8; Holland, Chris4,6; Blazier, John C.6,9; Sankararaman, Sriram7,10; Andolfatto, Peter11,12; Rosenthal, Gil G.4,6; Przeworski, Molly3,13 | |
2018-05-11 | |
发表期刊 | SCIENCE
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ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2018 |
卷号 | 360期号:6389页码:656-659 |
文章类型 | Article |
语种 | 英语 |
国家 | USA; Mexico; Denmark |
英文摘要 | To investigate the consequences of hybridization between species, we studied three replicate hybrid populations that formed naturally between two swordtail fish species, estimating their fine-scale genetic map and inferring ancestry along the genomes of 690 individuals. In all three populations, ancestry from the "minor" parental species is more common in regions of high recombination and where there is linkage to fewer putative targets of selection. The same patterns are apparent in a reanalysis of human and archaic admixture. These results support models in which ancestry from the minor parental species is more likely to persist when rapidly uncoupled from alleles that are deleterious in hybrids. Our analyses further indicate that selection on swordtail hybrids stems predominantly from deleterious combinations of epistatically interacting alleles. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000431790900046 |
WOS关键词 | GENE FLOW ; DELETERIOUS MUTATIONS ; SPECIATION ; NEANDERTHAL ; INCOMPATIBILITY ; HYBRIDIZATION ; STERILITY ; BARRIER ; MICE |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/198622 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Howard Hughes Med Inst, Boston, MA 02115 USA; 2.Harvard Univ, Harvard Soc Fellows, Cambridge, MA 02138 USA; 3.Columbia Univ, Dept Biol Sci, New York, NY 10027 USA; 4.Ctr Invest Cient Huastecas Aguaza, Calnali, Hidalgo, Mexico; 5.Univ Calif Berkeley, Ctr Computat Biol, Berkeley, CA 94720 USA; 6.Texas A&M Univ, Dept Biol, College Stn, TX 77843 USA; 7.Univ Calif Los Angeles, David Geffen Sch Med, Dept Human Genet, Los Angeles, CA 90095 USA; 8.Aarhus Univ, Bioinformat Res Ctr, Aarhus, Denmark; 9.Texas A&M Inst Genome Sci & Soc, College Stn, TX USA; 10.Univ Calif Los Angeles, Dept Comp Sci, Los Angeles, CA 90024 USA; 11.Princeton Univ, Dept Ecol & Evolutionary Biol, Princeton, NJ 08544 USA; 12.Princeton Univ, Lewis Sigler Inst Integrat Genom, Princeton, NJ 08544 USA; 13.Columbia Univ, Dept Syst Biol, New York, NY USA |
推荐引用方式 GB/T 7714 | Schumer, Molly,Xu, Chenling,Powell, Daniel L.,et al. Natural selection interacts with recombination to shape the evolution of hybrid genomes[J]. SCIENCE,2018,360(6389):656-659. |
APA | Schumer, Molly.,Xu, Chenling.,Powell, Daniel L..,Durvasula, Arun.,Skov, Laurits.,...&Przeworski, Molly.(2018).Natural selection interacts with recombination to shape the evolution of hybrid genomes.SCIENCE,360(6389),656-659. |
MLA | Schumer, Molly,et al."Natural selection interacts with recombination to shape the evolution of hybrid genomes".SCIENCE 360.6389(2018):656-659. |
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