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DOI | 10.1126/science.aao2189 |
Fractal-like hierarchical organization of bone begins at the nanoscale | |
Reznikov, Natalie1,2; Bilton, Matthew3,4; Lari, Leonardo3,5; Stevens, Molly M.1,2; Kroger, Roland3 | |
2018-05-04 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2018 |
卷号 | 360期号:6388页码:507-+ |
文章类型 | Article |
语种 | 英语 |
国家 | England; Canada |
英文摘要 | The components of bone assemble hierarchically to provide stiffness and toughness. However, the organization and relationship between bone's principal components-mineral and collagen-has not been clearly elucidated. Using three-dimensional electron tomography imaging and high-resolution two-dimensional electron microscopy, we demonstrate that bone mineral is hierarchically assembled beginning at the nanoscale: Needle-shaped mineral units merge laterally to form platelets, and these are further organized into stacks of roughly parallel platelets. These stacks coalesce into aggregates that exceed the lateral dimensions of the collagen fibrils and span adjacent fibrils as continuous, cross-fibrillar mineralization. On the basis of these observations, we present a structural model of hierarchy and continuity for the mineral phase, which contributes to the structural integrity of bone. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000431351500039 |
WOS关键词 | TRANSMISSION ELECTRON-MICROSCOPY ; AMORPHOUS CALCIUM-PHOSPHATE ; NUCLEAR-MAGNETIC-RESONANCE ; SOLID-STATE NMR ; LAMELLAR BONE ; CORTICAL BONE ; I COLLAGEN ; MINERALIZED TISSUES ; CRYSTAL-GROWTH ; Z-CONTRAST |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/198579 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Imperial Coll London, Fac Engn, Dept Mat, Dept Bioengn, London, England; 2.Imperial Coll London, Fac Engn, Inst Biomed Engn, London, England; 3.Univ York, Dept Phys, York, N Yorkshire, England; 4.Simon Fraser Univ, LABS 4D, Burnaby, BC, Canada; 5.York JEOL Nanoctr, Sci Pk, York, N Yorkshire, England |
推荐引用方式 GB/T 7714 | Reznikov, Natalie,Bilton, Matthew,Lari, Leonardo,et al. Fractal-like hierarchical organization of bone begins at the nanoscale[J]. SCIENCE,2018,360(6388):507-+. |
APA | Reznikov, Natalie,Bilton, Matthew,Lari, Leonardo,Stevens, Molly M.,&Kroger, Roland.(2018).Fractal-like hierarchical organization of bone begins at the nanoscale.SCIENCE,360(6388),507-+. |
MLA | Reznikov, Natalie,et al."Fractal-like hierarchical organization of bone begins at the nanoscale".SCIENCE 360.6388(2018):507-+. |
条目包含的文件 | 条目无相关文件。 |
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