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DOI | 10.1126/science.aan6203 |
Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus | |
Khodagholy, Dion1,2; Gelinas, Jennifer N.1,3,4; Buzsaki, Gyorgy1 | |
2017-10-20 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2017 |
卷号 | 358期号:6361页码:369-372 |
文章类型 | Article |
语种 | 英语 |
国家 | USA |
英文摘要 | Consolidation of declarative memories requires hippocampal-neocortical communication. Although experimental evidence supports the role of sharp-wave ripples in transferring hippocampal information to the neocortex, the exact cortical destinations and the physiologicalmechanisms of such transfer are not known. We used a conducting polymer-based conformable microelectrode array (NeuroGrid) to record local field potentials and neural spiking across the dorsal cortical surface of the rat brain, combined with silicon probe recordings in the hippocampus, to identify candidate physiological patterns. Parietal, midline, and prefrontal, but not primary cortical areas, displayed localized ripple (100 to 150 hertz) oscillations during sleep, concurrent with hippocampal ripples. Coupling between hippocampal and neocortical ripples was strengthened during sleep following learning. These findings suggest that ripple-ripple coupling supports hippocampal-association cortical transfer of memory traces. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000413251000043 |
WOS关键词 | HIGH-FREQUENCY OSCILLATIONS ; SHARP-WAVE-RIPPLE ; PARIETAL CORTEX ; SPATIAL MEMORY ; SLEEP ; RAT ; REORGANIZATION ; REACTIVATION ; INTEGRATION ; SUBREGIONS |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/197151 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.NYU, Neurosci Inst, Sch Med, New York, NY 10016 USA; 2.Columbia Univ, Dept Elect Engn, New York, NY 10027 USA; 3.Columbia Univ, Dept Neurol, Med Ctr, New York, NY 10032 USA; 4.Columbia Univ, Med Ctr, Inst Genom Med, New York, NY 10032 USA |
推荐引用方式 GB/T 7714 | Khodagholy, Dion,Gelinas, Jennifer N.,Buzsaki, Gyorgy. Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus[J]. SCIENCE,2017,358(6361):369-372. |
APA | Khodagholy, Dion,Gelinas, Jennifer N.,&Buzsaki, Gyorgy.(2017).Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus.SCIENCE,358(6361),369-372. |
MLA | Khodagholy, Dion,et al."Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus".SCIENCE 358.6361(2017):369-372. |
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