Global S&T Development Trend Analysis Platform of Resources and Environment
DOI | 10.1126/science.aan6245 |
MOF-derived cobalt nanoparticles catalyze a general synthesis of amines | |
Jagadeesh, Rajenahally V.1; Murugesan, Kathiravan1; Alshammari, Ahmad S.2; Neumann, Helfried1; Pohl, Marga-Martina1; Radnik, Joerg1; Beller, Matthias1 | |
2017-10-20 | |
发表期刊 | SCIENCE |
ISSN | 0036-8075 |
EISSN | 1095-9203 |
出版年 | 2017 |
卷号 | 358期号:6361页码:326-+ |
文章类型 | Article |
语种 | 英语 |
国家 | Germany; Saudi Arabia |
英文摘要 | The development of base metal catalysts for the synthesis of pharmaceutically relevant compounds remains an important goal of chemical research. Here, we report that cobalt nanoparticles encapsulated by a graphitic shell are broadly effective reductive amination catalysts. Their convenient and practical preparation entailed template assembly of cobalt-diamine- dicarboxylic acid metal organic frameworks on carbon and subsequent pyrolysis under inert atmosphere. The resulting stable and reusable catalysts were active for synthesis of primary, secondary, tertiary, and N-methylamines (more than 140 examples). The reaction couples easily accessible carbonyl compounds (aldehydes and ketones) with ammonia, amines, or nitro compounds, and molecular hydrogen under industrially viable and scalable conditions, offering cost-effective access to numerous amines, amino acid derivatives, and more complex drug targets. |
领域 | 地球科学 ; 气候变化 ; 资源环境 |
收录类别 | SCI-E |
WOS记录号 | WOS:000413251000033 |
WOS关键词 | METAL-ORGANIC FRAMEWORKS ; REDUCTIVE AMINATION ; CARBONYL-COMPOUNDS ; NITRO-COMPOUNDS ; POROUS CARBON ; HYDROGENATION ; KETONES ; ALDEHYDES ; AMMONIA ; NITROARENES |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
URL | 查看原文 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://119.78.100.173/C666/handle/2XK7JSWQ/197150 |
专题 | 地球科学 资源环境科学 气候变化 |
作者单位 | 1.Univ Rostock, Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany; 2.King Abdulaziz City Sci & Technol, POB 6086, Riyadh 11442, Saudi Arabia |
推荐引用方式 GB/T 7714 | Jagadeesh, Rajenahally V.,Murugesan, Kathiravan,Alshammari, Ahmad S.,et al. MOF-derived cobalt nanoparticles catalyze a general synthesis of amines[J]. SCIENCE,2017,358(6361):326-+. |
APA | Jagadeesh, Rajenahally V..,Murugesan, Kathiravan.,Alshammari, Ahmad S..,Neumann, Helfried.,Pohl, Marga-Martina.,...&Beller, Matthias.(2017).MOF-derived cobalt nanoparticles catalyze a general synthesis of amines.SCIENCE,358(6361),326-+. |
MLA | Jagadeesh, Rajenahally V.,et al."MOF-derived cobalt nanoparticles catalyze a general synthesis of amines".SCIENCE 358.6361(2017):326-+. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论